News

Healthtech Startup Avammune Bags $12 Mn From Capital 2B, Others

Publications

AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
Avijit Goswami, Barnali Deb, Sandeep Goyal, Abhishek Gosavi, Mukund Mali, Ashwita M. Martis, Princy Khurana, Mukesh Gangar, Digambar Raykar, Ankita Mohanty and Aditya Kulkarni

Molecules. October 2022, 27, 6721

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.
Mukesh Gangar, Sandeep Goyal, Digambar Raykar, Princy Khurana, Ashwita M. Martis, Avijit Goswami, Ishani Ghoshal, Ketul V. Patel, Yadav Nagare, Santosh Raikar, Apurba Mukherjee, Rajath Cyriac, Jean-François Paquin, Aditya Kulkarni

Bioorganic Chemistry. December 2021, 0045-2068/© 2021 Elsevier Inc.

Conference Abstracts

809 Exploring the therapeutic benefit of AVA-NP-695 (ENPP1 inhibitor) and DNA damage inhibition to activation of the immune system in metastatic osteosarcoma
Borja Ruiz Fernandez de Cordoba, Avijit Goswami, Sandeep Goyal, Kawaljit Singh, Princy Khurana, Aditya Kulkarni, Alejandro Sweet-Cordero

Journal for ImmunoTherapy of Cancer Nov 2024, 12 (Suppl 2) A914; DOI:10.1136/jitc-2024-SITC2024.0809

740 Discovery of a potential first-in-class inhibitor targeting ADAR1 p150 isoform with strong anti-tumor efficacy in syngeneic melanoma mouse model
Avijit Goswami, Sandeep Goyal, Kawaljit Singh, Princy Khurana, Aditya Kulkarni

Journal for ImmunoTherapy of Cancer Nov 2024, 12 (Suppl 2) A843; DOI:10.1136/jitc-2024-SITC2024.0740

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