Multi-Modal Cancer Therapies

Avammune develops first-in-class and best-in-class
small-molecule therapeutics across foundational therapeutic modalities in oncology, enabling early POC-driven partnerships for the development of pioneering medicines.

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Our Platform

From Target Selection to Durable Anti-tumor Responses

Bioinformatics and computational chemistry-driven target ID and drug design

Proprietary library of molecules that target DNA/RNA-binding proteins

High throughput chemistry and biology for rapid turnaround cycles

Experienced team, lean programs, rapid clinical translation

Our Modalities

Multi-Pronged Approach for Cancer Cure

Immune Modulation

Reshaping immune landscape in the tumor microenvironment to convert non-responsive ‘cold’ tumors into immune-responsive ‘hot’ tumors

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Next-Generation Targeted Therapies

Turning critical cancer dependencies into therapeutic opportunities

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Targeted Cancer Cell Killing Modalities

Using targeted radiotherapeutics to directly kill tumor cells while sparing healthy tissues.

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About Us

Building the
Next Generation of
Oncology Therapies

Avammune is an R&D-driven drug discovery company developing novel modality-agnostic best-in-class and first-in-class therapies for hard-to-treat solid tumors.

Our team brings deep expertise across medicinal chemistry, immunology, discovery biology, and computational chemistry, with a track record of scientific innovation, IP creation, and successful exits. 

Meet Our Team
We collaborate to co-develop oncology assets, accelerate preclinical programs, and expand access to next-generation cancer therapeutics.
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Designed for

Collaborative Development

Publications

AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
Avijit Goswami, Barnali Deb, Sandeep Goyal, Abhishek Gosavi, Mukund Mali, Ashwita M. Martis, Princy Khurana, Mukesh Gangar, Digambar Raykar, Ankita Mohanty and Aditya Kulkarni

Molecules. October 2022, 27, 6721

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.
Mukesh Gangar, Sandeep Goyal, Digambar Raykar, Princy Khurana, Ashwita M. Martis, Avijit Goswami, Ishani Ghoshal, Ketul V. Patel, Yadav Nagare, Santosh Raikar, Apurba Mukherjee, Rajath Cyriac, Jean-François Paquin, Aditya Kulkarni

Bioorganic Chemistry. December 2021, 0045-2068/© 2021 Elsevier Inc.